genetic mutation
noun
plural genetic mutations
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.—
Natalie Angier
Natalie AngierExamples of genetic mutation in a Sentence
Recent Examples on the Web
People who work in rubber or coal industries may breathe in harmful chemicals that increase the risk of genetic mutations.
—Carrie Madormo, Health, 17 Oct. 2025
Further testing confirmed that the genetic changes came from within the phage itself, as the host remained unchanged when viral genetic mutations were knocked out.
—New Atlas, 16 Oct. 2025
That’s why two people with the same genetic mutation can seem so different.
—Santhosh Girirajan, The Conversation, 7 Oct. 2025
Elements that increase risk include a history of radiation to the chest, certain genetic mutations, and having a first-degree relative (like a mother or sister) with breast cancer.
—Katia Hetter, CNN Money, 1 Oct. 2025
See All Example Sentences for genetic mutation
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Carrie Madormo, Health, 17 Oct. 2025
Further testing confirmed that the genetic changes came from within the phage itself, as the host remained unchanged when viral genetic mutations were knocked out.
—New Atlas, 16 Oct. 2025
That’s why two people with the same genetic mutation can seem so different.
—Santhosh Girirajan, The Conversation, 7 Oct. 2025
Elements that increase risk include a history of radiation to the chest, certain genetic mutations, and having a first-degree relative (like a mother or sister) with breast cancer.
—Katia Hetter, CNN Money, 1 Oct. 2025
See All Example Sentences for genetic mutation
Cite this Entry
“Genetic mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genetic%20mutation. Accessed 24 Oct. 2025.
Copy CitationMedical Definition
genetic mutation
noun
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.—Joseph Alper
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